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Ultrasound-assisted Extraction of Cannabinoids

The ultrasonic extractors (often called ultrasonic emulsifiers) are the latest scientific devices being used to obtain CBD from hemp.
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  • RPS-SONO20

  • Rps-sonic

  • RPS-SONO20

Ultrasound-assisted Extraction of Cannabinoids


CBD has become a wildly popular herbal supplement, but many users simply don’t know how the plant extract is created. There are many ways to extract CBD from the cannabis plant. CBD can be extracted from the hemp plant’s fibers through any of these methods: carbon dioxide, hydrocarbon, natural solvents, and steam distillation. Ultrasonic is a key tool for most the the extraction methods.

The Medicinal Community and Ultrasonic Extraction

Ultrasonic extraction is considered the wave of the future when it comes to the successful extraction of cannabinoids from hemp. The medicinal cannabis industry has started to turn to the advanced method as one of the best ways to obtain viable therapeutic compounds successfully from the cannabis plant fibers. It is a clean method that leaves no solvent residue.



Parameter

Model

SONO20-1000

SONO20-2000

SONO15-3000

SONO20-3000

Frequency

20±0.5 KHz

20±0.5 KHz

15±0.5 KHz

20±0.5 KHz

Power

1000 W

2000 W

3000 W

3000 W

Voltage

220/110V

220/110V

220/110V

220/110V

Temperature

300 ℃

300 ℃

300 ℃

300 ℃

Pressure

35 MPa

35 MPa

35 MPa

35 MPa

Intensity of sound

20 W/cm²

40 W/cm²

60 W/cm²

60 W/cm²

Max Capacity

10 L/Min

15 L/Min

20 L/Min

20 L/Min

Tip Head Material

Titanium Alloy

Titanium Alloy

Titanium Alloy

Titanium Alloy




How Does Ultrasound Extraction Work?

Water ultrasonic extraction relies on ultrasonic waves (referred to as sonication) to pull the cannabinoids from the plant fibers. An environmentally friendly extraction method, it does not use harsh solvents. Another perk is that it takes only minutes to obtain the cannabinoids compared to other methods which take from hours to days to obtain the extraction. Depending on the ultrasonic extractor, it can be easily modified to work with a wide array of solvents such as CO2, H20, coconut oil, olive oil, ethanol, and warm water.


No Heat Extraction

Another benefit of ultrasonic extractors is that they don’t rely on heat, so the cannabinoids and terpenes of the plants are never broken down or destroyed by hot temperatures. Most extraction methods rely on remarkably high heat which may destroy cannabinoid potency and can have a significant impact on the effectiveness of the whole plant cannabinoid’s medicinal value. Luckily, the method is extremely low thermal and does not require temperatures more than 140° F (60°C).


Breaking Through the Cellular Walls

With ultrasonic extraction the problem is that THC and CBD are hydrophobic . Typically, harsh solvents have been required to pull the cannabinoids from the cell walls. Bioavailability has been a problem in the breakdown of the tough cellular wall so finding the perfect extraction method has been challenging. With ultrasonic extraction, the sonication uses ultrasonic waves. A probe is inserted into the mixture. The probe starts to put forth both high and low pressure sound waves. The waves create microscopic currents and pressurized liquid eddies which creates a harsh environment. The speed of the waves goes at speeds of 20,000 per second which effectively bust through the cell walls. The sheer force creates a pressurized atmosphere. Millions of tiny bubbles form that start to pop and effectively break down the cell wall. Once the cell wall breaks, the inner material is released which creates a powerful emulsion.



ultrasonic extraction

IMG_2658




Sonochemical reactions

Three classes of sonochemical reactions exist: homogeneous sonochemistry of liquids, heterogeneous sonochemistry of liquid-liquid or solid–liquid systems, and, overlapping with the aforementioned, sonocatalysis (the catalysis or increasing the rate of a chemical reaction with ultrasound). Sonoluminescence is a consequence of the same cavitation phenomena that is responsible for homogeneous sonochemistry. The chemical enhancement of reactions by ultrasound has been explored and has beneficial applications in mixed phase synthesis, materials chemistry, and biomedical uses. Because cavitation can only occur in liquids, chemical reactions are not seen in the ultrasonic irradiation of solids or solid–gas systems.

For example, in chemical kinetics, it has been observed that ultrasound can greatly enhance chemical reactivity in a number of systems by as much as a million-fold;[16] effectively acting to activate heterogeneous catalysts. In addition, in reactions at liquid-solid interfaces, ultrasound breaks up the solid pieces and exposes active clean surfaces through microjet pitting from cavitation near the surfaces and from fragmentation of solids by cavitation collapse nearby. This gives the solid reactant a larger surface area of active surfaces for the reaction to proceed over, increasing the observed rate of reaction. 

While the application of ultrasound often generates mixtures of products, a paper published in 2007 in the journal Nature described the use of ultrasound to selectively affect a certain cyclobutane ring-opening reaction. Atul Kumar has reported multicomponent reaction Hantzsch ester synthesis in Aqueous Micelles using ultrasound.

Some water pollutants, especially chlorinated organic compounds, can be destroyed sonochemically.

Sonochemistry can be performed by using a bath (usually used for ultrasonic cleaning) or with a high power probe, called an ultrasonic horn, which funnels and couples a piezoelectric element's energy int


See also

Ultrasound

Sonication

Ultrasonics

ultrasonic homogenizer

homogenizer

Homogenization (chemistry)

Sonoelectrochemistry

Kenneth S. Suslick


1. Can your sonochemistry horn be used in an acid (alkali) environment?

Under the acid (alkali) environment, the horn need to be customized according to the actual working conditions of customers.

 

2. Can the ultrasonic sonochemistry work continuously?

Yes , it can work 24hours continue.

 

3. What kind of material is the horn?

Titanium alloy, we also  customized ceramic horn for customer before.

 

4. What’s the time of delivery

 For Conventional horn, 3 days, for customized horn 7 work days.

 

5. Does ultrasonic extraction also require the addition of a chemical catalyst?

No , but some time need Mechanical stirring.

 

6. What’s the advantage of ultrasonic extraction?

Decline the extraction time, and increase the extraction ratio.

 

7. What’s the Processing capacity of one set ultrasonic extraction equipment?

Different horn different Processing capacity, for 2000W Nine-section whip horn can dealing 2L~10L/min.

 

8. Are you manufacturer?

We only manufacturer the transducer and generator our-self, for the horn , we design and buy raw material ,and process by other companies.

 

9. What’s the warranty of your sonochemistry equipment?

All equipment one year warranty.

 

10. Do you have Foreign agent?

No, our price already very low for everyone, no agent. We have OEM customer in USA and Germany.

 

11. Is it difficult to install the ultrasonic sonochemistry equipment?

No , it is easy , we will share Installation diagram, also can take install video for you.


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 Ms. Yvonne
  sales@xingultrasonic.com   
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