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Ultrasonic Cell Pulverizer High Power 20Khz for Extraction of Polygonatum Polysaccharide

Ultrasonic Cell Disruptors also called Ultrasonic Homogenizers, Ultrasonic Homogenizerscan prepare emulsions down to 1/100 of a micron, homogenize "immiscible" liquids, accelerate enzymatic and chemical reactions, stimulate bacterial activity, disperse solids in liquids and degas liquids.
Generator :
  • RPS-SONO20
  • Rps-sonic
  • RPS-SONO20

Ultrasonic Cell Pulverizer High Power 20Khz for Extraction of Polygonatum Polysaccharide

What's the theory of ultrasonic Cell Pulverizer

Ultrasonic is an elastic mechanical wave in a matter medium, which is a form of wave, so it can be used to detect physiological and pathological information of the human body, and to diagnose ultrasound. At the same time, it is a form of energy. When a certain dose of ultrasound is transmitted in the living body, the interaction between the two can cause the function and structure of the organism to change, that is, the ultrasonic biological effect. The effects of ultrasound on cells are mainly thermal effects, cavitation effects and mechanical effects. The thermal effect is that when the ultrasound propagates through the medium, the friction hinders the molecular vibration caused by the ultrasound, converting part of the energy into local high heat (42-43 ° C), because the critical lethal temperature of normal tissue is 45.7 ° C, and the tumor tissue ratio Normal tissue sensitivity is high, so at this temperature, the metabolism of tumor cells is impaired, DNA, RNA, and protein synthesis are affected, thereby killing cancer cells and normal tissues are not affected. The cavitation effect is that under the irradiation of ultrasound, vacuoles are formed in the living body, and mechanical shear pressure and turbulence are generated along with the vibration of the vacuole and its violent explosion, which causes the tumor to hemorrhage and the tissue to collapse and cause necrosis. In addition, when the cavitation bubble bursts, it generates instantaneous high temperature (about 5000 ° C) and high pressure (up to 500 × 104 Pa), which can thermally dissociate the water vapor to produce .OH radicals and .H atoms, which are composed of .OH radicals and .H. Atomic induced redox reactions can lead to polymer degradation, enzyme inactivation, lipid peroxidation, and cell killing. The mechanical effect is the primary effect of ultrasound. During the propagation process, the medium particles alternately compress and stretch to form a pressure change, causing damage to the cell structure. The intensity of killing is closely related to the frequency and intensity of ultrasound.








20±0.5 KHz

20±0.5 KHz

28±0.5 KHz

40±0.5 KHz


300 W

500 W

300 W

100 W







300 ℃

300 ℃

300 ℃

300 ℃


35 MPa

35 MPa

35 MPa

35 MPa

Max Capacity

2 L/Min

5 L/Min


0.5 L/Min

Tip Head Material

Titanium Alloy

Titanium Alloy

Titanium Alloy

Titanium Alloy


Ultrasonic Cell Pulverizer High Power 20Khz for Extraction of Polygonatum Polysaccharide used in a variety of animal and plant cells, virus cells, bacteria, dental spores and tissue ultrasonic extraction method using ultrasonic waves, its powerful cavitation effect and many secondary effects such as: mechanical vibration, crushing emulsification, diffusion, etc. can break the cell wall release Substance, commonly used in the breakdown of various animal and plant cells, viral cells, bacteria, spores and tissues. In this study, ultrasonic polysaccharide cell pulverizer was used to extract Polygonatum polysaccharide. The obtained polysaccharide was lighter in color, less impurities and higher purity than water decoction and dilute alkali extraction. It is an effective method for extracting Polygonatum polysaccharide.

Ultrasonic Cell Pulverizer

Sonochemical reactions

Three classes of sonochemical reactions exist: homogeneous sonochemistry of liquids, heterogeneous sonochemistry of liquid-liquid or solid–liquid systems, and, overlapping with the aforementioned, sonocatalysis (the catalysis or increasing the rate of a chemical reaction with ultrasound). Sonoluminescence is a consequence of the same cavitation phenomena that is responsible for homogeneous sonochemistry. The chemical enhancement of reactions by ultrasound has been explored and has beneficial applications in mixed phase synthesis, materials chemistry, and biomedical uses. Because cavitation can only occur in liquids, chemical reactions are not seen in the ultrasonic irradiation of solids or solid–gas systems.

For example, in chemical kinetics, it has been observed that ultrasound can greatly enhance chemical reactivity in a number of systems by as much as a million-fold;[16] effectively acting to activate heterogeneous catalysts. In addition, in reactions at liquid-solid interfaces, ultrasound breaks up the solid pieces and exposes active clean surfaces through microjet pitting from cavitation near the surfaces and from fragmentation of solids by cavitation collapse nearby. This gives the solid reactant a larger surface area of active surfaces for the reaction to proceed over, increasing the observed rate of reaction. 

While the application of ultrasound often generates mixtures of products, a paper published in 2007 in the journal Nature described the use of ultrasound to selectively affect a certain cyclobutane ring-opening reaction. Atul Kumar has reported multicomponent reaction Hantzsch ester synthesis in Aqueous Micelles using ultrasound.

Some water pollutants, especially chlorinated organic compounds, can be destroyed sonochemically.

Sonochemistry can be performed by using a bath (usually used for ultrasonic cleaning) or with a high power probe, called an ultrasonic horn, which funnels and couples a piezoelectric element's energy int

See also




ultrasonic homogenizer


Homogenization (chemistry)


Kenneth S. Suslick

1. Can your sonochemistry horn be used in an acid (alkali) environment?

Under the acid (alkali) environment, the horn need to be customized according to the actual working conditions of customers.


2. Can the ultrasonic sonochemistry work continuously?

Yes , it can work 24hours continue.


3. What kind of material is the horn?

Titanium alloy, we also  customized ceramic horn for customer before.


4. What’s the time of delivery

 For Conventional horn, 3 days, for customized horn 7 work days.


5. Does ultrasonic extraction also require the addition of a chemical catalyst?

No , but some time need Mechanical stirring.


6. What’s the advantage of ultrasonic extraction?

Decline the extraction time, and increase the extraction ratio.


7. What’s the Processing capacity of one set ultrasonic extraction equipment?

Different horn different Processing capacity, for 2000W Nine-section whip horn can dealing 2L~10L/min.


8. Are you manufacturer?

We only manufacturer the transducer and generator our-self, for the horn , we design and buy raw material ,and process by other companies.


9. What’s the warranty of your sonochemistry equipment?

All equipment one year warranty.


10. Do you have Foreign agent?

No, our price already very low for everyone, no agent. We have OEM customer in USA and Germany.


11. Is it difficult to install the ultrasonic sonochemistry equipment?

No , it is easy , we will share Installation diagram, also can take install video for you.

Get in touch




 Ms. Yvonne
  sales@xingultrasonic.com   
   Room 1103B, Nature business building ,  NO.1160 GongWang Road ,FuYang, Hangzhou,Zhejiang,China